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mRNA 1647

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Drug Profile

mRNA 1647

Alternative Names: CMV vaccine - Moderna Therapeutics; Cytomegalovirus vaccine - Moderna Therapeutics; mRNA-1647

Latest Information Update: 13 Feb 2026

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At a glance

  • Originator Moderna Therapeutics
  • Class Cytomegalovirus vaccines; RNA vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Cytomegalovirus infections

Most Recent Events

  • 19 Jan 2026 Moderna Therapeutics completes a phase II long-term extension trial in Cytomegalovirus infections (Prevention) in USA (IM) (NCT04975893)
  • 06 Dec 2025 Immunogenicity data from phase I trial in healthy volunteers presented at the 67th American Society of Hematology Annual Meeting and Exposition (ASH-2025)
  • 20 Nov 2025 Discontinued - Phase-I/II for Cytomegalovirus infections (In adolescents, In children, Prevention, In adults) in United Kingdom (IM) due to strategic prioritization

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