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NGM 120

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Drug Profile

NGM 120

Alternative Names: NGM-120

Latest Information Update: 14 Mar 2024

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At a glance

  • Originator NGM Biopharmaceuticals
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Growth differentiation factor 15 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Cachexia
  • Suspended Pancreatic cancer; Solid tumours

Most Recent Events

  • 11 Mar 2024 NGM Biopharmaceuticals plans a phase-II trial for Hyperemesis gravidarum by the end of 2024
  • 09 Jan 2024 Suspended - Phase-I/II for Solid tumours (Late-stage disease, Metastatic disease, Monotherapy) in USA (SC), since a clear signal of response was not detected
  • 09 Jan 2024 Suspended - Phase-II for Pancreatic cancer (Combination therapy, Inoperable/Unresectable, Metastatic disease, Recurrent, Second-line therapy or greater) in USA (SC), since a clear signal of response was not detected

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