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Atuzaginstat - Quince Therapeutics

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Drug Profile

Atuzaginstat - Quince Therapeutics

Alternative Names: COR-388; COR388-HCl

Latest Information Update: 28 Mar 2026

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At a glance

  • Originator Cortexyme
  • Developer Quince Therapeutics
  • Class Anti-inflammatories; Antibacterials; Antidementias; Antineoplastics; Antiparkinsonians; Neuroprotectants; Small molecules
  • Mechanism of Action Gingipain cysteine endopeptidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II/III Alzheimer's disease
  • Phase II Periodontal disorders
  • No development reported Parkinson's disease; Squamous cell cancer

Most Recent Events

  • 28 Mar 2026 No recent reports of development identified for preclinical development in Squamous-cell-cancer in USA
  • 28 Feb 2025 No recent reports of development identified for preclinical development in Parkinson's-disease in USA (PO)
  • 27 Jan 2023 COR 388 licensed to Lighthouse Pharmaceuticals in the US

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