Research programme: dihydroorotate dehydrogenase inhibitors - Agios Pharmaceuticals

Drug Profile

Research programme: dihydroorotate dehydrogenase inhibitors - Agios Pharmaceuticals

Alternative Names: DHODH inhibitor - Agios Pharmaceuticals; Dihydrooroate dehydrogenase inhibitor - Agios Pharmaceuticals

Latest Information Update: 15 Jan 2018

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At a glance

  • Originator Agios Pharmaceuticals
  • Class Antineoplastics
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Haematological malignancies

Most Recent Events

  • 15 Jan 2018 Preclinical development in Haematological malignancies in USA (unspecified route)
  • 15 Jan 2018 Agios Pharmaceuticals plans to file an IND application for dihydrooroate dehydrogenase inhibitor for haematological malignancies in the fourth quarter of 2018
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