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Orludodstat - Bayer

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Drug Profile

Orludodstat - Bayer

Alternative Names: BAY-2402234

Latest Information Update: 28 May 2025

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At a glance

  • Originator Broad Institute
  • Developer Bayer
  • Class Antineoplastics; Benzamides; Halogenated hydrocarbons; Phenyl ethers; Small molecules; Triazoles
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Mesothelioma
  • No development reported Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Colorectal cancer; Lymphoma; Myelodysplastic syndromes; Small cell lung cancer

Most Recent Events

  • 28 May 2025 No recent reports of development identified for preclinical development in Small-cell-lung-cancer in Germany (PO)
  • 25 Apr 2025 Preclinical trials in Mesothelioma in Germany (unspecified route) prior to April 2025
  • 25 Apr 2025 Pharmacodynamics and pharmacokinetics data from a preclinical study in Mesothelioma presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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