Epcoritamab - Genmab/AbbVie
Alternative Names: ABBV-GMAB-3013; Anti-CD3 anti-CD20 bispecific antibody - Genmab/AbbVie; Duobody-CD3-CD20; DuoBody-CD3xCD20; Epcoritamab-bysp; EPKINLY; GEN-3013; TEPKINLYLatest Information Update: 12 Oct 2026
At a glance
- Originator Genmab
- Developer AbbVie; Genmab
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants
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Orphan Drug Status
Yes - Follicular lymphoma
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Diffuse large B cell lymphoma; Follicular lymphoma
- Phase II Non-Hodgkin's lymphoma
- Phase I/II B-cell lymphoma; Chronic lymphocytic leukaemia; Haematological malignancies; Richter's syndrome
Most Recent Events
- 05 Oct 2026 Efficacy and adverse events data form phase III clinical trials in Diffuse large B cell lymphoma released by AbbVie
- 05 Oct 2026 Efficacy and adverse event data from the phase III EPCORE DLBCL-2 trial for Diffuse large B-cell lymphoma released by AbbVie
- 24 Sep 2026 Registered for Follicular lymphoma (Combination therapy, Second-line therapy or greater) in Canada (SC)