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Talquetamab - Genmab/Janssen Research & Development

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Drug Profile

Talquetamab - Genmab/Janssen Research & Development

Alternative Names: GPRC5D/CD3-duobody-antibody-JNJ-64407564; JNJ 64407564; JNJ-7564; TALVEY

Latest Information Update: 18 Jul 2025

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At a glance

  • Originator Genmab; Janssen Research & Development
  • Developer Janssen Research & Development
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Multiple myeloma
  • Phase II Smoldering multiple myeloma

Most Recent Events

  • 24 Jun 2025 Registered for Multiple myeloma (Second-line therapy or greater) in Japan (SC)
  • 16 Jun 2025 Adverse events and efficacy data from a phase I/II RedirecTT-1 trial in Multiple myeloma released by Janssen Pharmaceuticals
  • 03 Feb 2025 Phase-III clinical trials in Multiple myeloma (First-line therapy, Combination therapy) in USA (SC) (NCT05552222)

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