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Nefextinib - Maxinovel Pharmaceuticals

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Drug Profile

Nefextinib - Maxinovel Pharmaceuticals

Alternative Names: Max 4; MAX-40279; MAX-40279-001; MAX-40279-01; Max-5; Max-6; Multi-target tyrosine kinase inhibitor - Maxinovel

Latest Information Update: 31 Jan 2026

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At a glance

  • Originator Maxinovel Pharmaceuticals
  • Class 2 ring heterocyclic compounds; Amines; Anisoles; Antifibrotics; Antineoplastics; Fluorobenzenes; Piperidines; Pyrazoles; Pyrimidines; Small molecules; Thiophenes
  • Mechanism of Action Fibroblast growth factor receptor antagonists; Fms-like tyrosine kinase 3 inhibitors; Hematopoietic progenitor kinase 1 inhibitors; Janus kinase inhibitors; Platelet-derived growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Gastric cancer; Idiopathic pulmonary fibrosis; Oesophageal cancer
  • Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes
  • No development reported Solid tumours

Most Recent Events

  • 31 Jan 2026 Chemical structure information added.
  • 28 Jan 2026 Phase-II clinical trials in Idiopathic pulmonary fibrosis in China (PO) before January 2026 (Maxinovel pipeline, January 2026)
  • 28 May 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Metastatic disease) in China (PO)

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