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PL 8177

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Drug Profile

PL 8177

Alternative Names: PL-8177

Latest Information Update: 11 Apr 2025

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At a glance

  • Originator Palatin Technologies
  • Class Anti-inflammatories; Cyclic peptides; Eye disorder therapies; Peptides
  • Mechanism of Action Melanocortin type 1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Uveitis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Inflammatory bowel diseases; Ulcerative colitis
  • Preclinical Arthritis; Diabetic nephropathies; Diabetic retinopathy
  • No development reported COVID 2019 infections; Nephritis; Uveitis

Most Recent Events

  • 28 Mar 2025 Adverse events and efficacy data from a phase II trial for ulcerative colitis released by Palatin Technologies
  • 25 Nov 2024 Palatin completes enrolment in its phase II trial for Ulcerative colitis in USA (PO) (NCT05466890)
  • 16 Oct 2023 Pharmacodynamics data from a preclinical trial in Inflammatory bowel disease released by Palatin Technologies

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