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BBO 11818

Drug Profile

BBO 11818

Alternative Names: BBO-11818; Pan-KRAS inhibitor - BridgeBio Pharma

Latest Information Update: 16 Mar 2026

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At a glance

  • Originator BridgeBio Pharma
  • Developer BridgeBio Oncology Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 06 Mar 2026 Pharmacodynamics data from a preclinical trial in Solid tumours released by the BridgeBio Oncology Therapeutics
  • 07 Jan 2026 BridgeBio Pharma plans a combination trial with BBO 10203 later in 2026
  • 07 Jan 2026 Efficacy, pharmacokinetics and adverse events data from a phase Ia/Ib trial in Solid tumours released by BridgeBio Pharma

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