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ADX 629

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Drug Profile

ADX 629

Alternative Names: ADX-629

Latest Information Update: 04 Nov 2025

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At a glance

  • Originator Aldeyra Therapeutics
  • Class Anti-inflammatories; Antiallergics; Antipsoriatics; Antitussives; Antivirals; Hepatoprotectants; Skin disorder therapies; Small molecules
  • Mechanism of Action Aldehyde inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alcoholic hepatitis; Alcoholism; Allergic asthma; Atopic dermatitis; Cough; Cytokine release syndrome; Lipoid nephrosis; Nephrotic syndrome; Plaque psoriasis; SARS-CoV-2 acute respiratory disease; Sjogren-Larsson syndrome

Most Recent Events

  • 04 Nov 2025 Discontinued - Phase-I/II for Sjogren-Larsson syndrome in USA (PO)
  • 04 Nov 2025 Discontinued - Phase-II for Alcoholic hepatitis (In adults, In the elderly) in USA (PO)
  • 04 Nov 2025 Discontinued - Phase-II for Alcoholism in USA (PO)

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