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Cavrotolimod - Mirum Pharmaceuticals

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Drug Profile

Cavrotolimod - Mirum Pharmaceuticals

Alternative Names: AST 008

Latest Information Update: 06 Feb 2026

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At a glance

  • Originator Exicure
  • Developer Exicure; Mirum Pharmaceuticals
  • Class Antineoplastics; Antivirals; Immunotherapies; Oligonucleotides
  • Mechanism of Action Immunostimulants; Toll-like receptor 9 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Merkel cell carcinoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Hepatitis B
  • Discontinued Haematological malignancies; Merkel cell carcinoma; Solid tumours; Squamous cell cancer

Most Recent Events

  • 26 Jan 2026 Bluejay Therapeutics has been acquired and merged into Mirum Pharmaceuticals
  • 15 Nov 2024 Pharmacodynamics data from preclinical studies in Hepatitis B presented at the 75th Annual Meeting of the American Association for the Study of Liver Diseases cynomolgus monkeys (AASLD-2024)
  • 15 Nov 2024 Pharmacodynamics data from the preclinical studies in Hepatitis B released by Bluejay Therapeutics

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