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Treprostinil dry powder inhalation - MannKind Corporation/United Therapeutics Corporation

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Drug Profile

Treprostinil dry powder inhalation - MannKind Corporation/United Therapeutics Corporation

Alternative Names: Treprostinil Technosphere®; TreT; Tyvaso DPI

Latest Information Update: 21 Jul 2024

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At a glance

  • Originator MannKind Corporation
  • Developer United Therapeutics Corporation
  • Class Acetic acids; Antifibrotics; Antihypertensives; Cyclopentanes; Naphthalenes; Prostaglandins; Skin disorder therapies; Small molecules; Vasodilators
  • Mechanism of Action Epoprostenol receptor agonists; Platelet aggregation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Pulmonary arterial hypertension; Pulmonary hypertension

Most Recent Events

  • 10 Jul 2024 United Therapeutics announces intention to seek US FDA approval to expand the Tyvaso DPI label to includeIdiopathic pulmonary fibrosis and Pulmonary arterial hypertension completion of the TETON studies
  • 22 Aug 2023 United Therapeutics completes the phase-I BREEZE trial in Pulmonary arterial hypertension (Treatment experienced) in USA (Inhalation) (NCT03950739),
  • 28 Oct 2022 No recent reports of development identified for phase-I development in Pulmonary-arterial-hypertension(In the elderly, Treatment-experienced, In adults) in USA (Inhalation, Powder)

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