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Pirfenidone inhalation - Avalyn Pharmaceuticals

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Drug Profile

Pirfenidone inhalation - Avalyn Pharmaceuticals

Alternative Names: Aerodone; AP 01; GP 101

Latest Information Update: 02 Dec 2024

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At a glance

  • Originator Avalyn Pharma
  • Class Anti-inflammatories; Antifibrotics; Heart failure therapies; Pyridones; Small molecules
  • Mechanism of Action Collagen inhibitors; Cytokine inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity No

Highest Development Phases

  • Phase II Idiopathic pulmonary fibrosis; Interstitial lung diseases; Pulmonary fibrosis

Most Recent Events

  • 19 Nov 2024 Phase-II clinical trials in Pulmonary fibrosis (Treatment-experienced) in Argentina, Australia, Canada, France, Italy, Germany, New Zealand, Poland, United Kingdom (Inhalation) (NCT06329401)
  • 07 Sep 2024 Adverse event and pharmacodynamics data from the phase I/II ATLAS trial in Idiopathic pulmonary fibrosis presented at the 34th Annual Congress of the European Respiratory Society 2024 (ERS-2024)
  • 20 May 2024 Efficacy and adverse events data from the phase I/II ATLAS trial in Idiopathic pulmonary fibrosis presented at the International Conference of the American Thoracic Society (ATS-2024)

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