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ZN e4

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Drug Profile

ZN e4

Alternative Names: ZN-e4

Latest Information Update: 12 Dec 2022

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At a glance

  • Originator Zentalis Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Non-small cell lung cancer

Most Recent Events

  • 15 Nov 2022 Zeno Pharmaceuticals completes its phase I/II trial in Non-small cell lung cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Bosnia-Herzegovina and USA (PO) (NCT03446417)
  • 09 Sep 2022 Zentalis Pharmaceuticals plans to discontinue the clinical development of ZN e4 in Non-small cell lung cancer (Zentalis Pharmaceuticals pipeline, September 2022)
  • 17 Mar 2021 ZN e4 is still in phase I/II trials for Non-small cell lung cancer in USA (NCT03446417)

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