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PBF 1129

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Drug Profile

PBF 1129

Alternative Names: PBF-1129

Latest Information Update: 17 Jun 2025

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At a glance

  • Originator Palobiofarma
  • Developer Ohio State University; Palobiofarma
  • Class Antifibrotics; Antineoplastics
  • Mechanism of Action Adenosine A2B receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • No development reported Idiopathic pulmonary fibrosis

Most Recent Events

  • 25 Apr 2025 Adverse events, efficacy and pharmacodynamic data from a phase I trial in Non-small cell lung cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 28 Feb 2025 No recent reports of development identified for phase-I development in Idiopathic-pulmonary-fibrosis in Spain (PO)
  • 17 Jul 2023 Phase-II clinical trials in Non-small cell lung cancer (Late-stage disease, Metastatic disease) in USA (PO) prior to July 2023 (Palobiofarma pipeline, July 2023)

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