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S 095033

Drug Profile

S 095033

Alternative Names: AG-270; S-095033; S-95033

Latest Information Update: 07 Jul 2023

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At a glance

  • Originator Agios Pharmaceuticals
  • Developer Agios Pharmaceuticals; Servier
  • Class Antineoplastics; Ethers; Ketones; Morpholines; Pyridazines; Small molecules
  • Mechanism of Action MAT2A protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Adenocarcinoma; Squamous cell cancer
  • Phase I Lymphoma; Solid tumours

Most Recent Events

  • 26 Jun 2023 Agios Pharmaceuticals terminates a phase I trial in Lymphoma, Solid tumours (Late-stage disease, Second-line therapy or greater, Monotherapy, Combination therapy) in USA, Spain, France (PO) (NCT03435250)
  • 20 Apr 2023 Agios Pharmaceuticals completes a phase I trial in Lymphoma, Solid tumours (Late-stage disease, Second-line therapy or greater, Monotherapy, Combination therapy) in USA, Spain, France (PO) (NCT03435250)
  • 07 Dec 2022 Institut de Recherches Internationales Servier in collaboration with Servier withdrews a phase I/II trial prior to enrollment in Oesophageal cancer (Combination therapy) (Late stage disease) (Metastatic disease) (IV) due to strategic development reasons (NCT05312372)
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