Drug Profile

NYX 458

Alternative Names: NYX-458

Latest Information Update: 27 Mar 2023

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At a glance

Originator Aptinyx
Class Antiparkinsonians; Neuroprotectants; Nootropics; Small molecules
Mechanism of Action NMDA receptor modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Cognition disorders; Parkinson's disease

Most Recent Events

27 Feb 2023 Discontinued - Phase-II for Cognition disorders in USA (PO)
27 Feb 2023 Discontinued - Phase-II for Parkinson's disease in USA (PO)
27 Feb 2023 Pharmacodynamics and adverse events data from a phase II trial in Cognition disorders and Parkinson's disease released by Aptinyx

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