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Ligufalimab - Akeso Biopharma

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Drug Profile

Ligufalimab - Akeso Biopharma

Alternative Names: AK-117

Latest Information Update: 23 Jun 2026

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At a glance

  • Originator Akeso Biopharma
  • Developer Akeso Biopharma; University of Texas Southwestern Medical Center
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD47 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Adenocarcinoma; Squamous cell cancer
  • Phase II Cholangiocarcinoma; Colorectal cancer; Gastric cancer; Liver cancer; Myelodysplastic syndromes; Oesophageal cancer; Triple negative breast cancer
  • Phase I/II Acute myeloid leukaemia; Hodgkin's disease; Solid tumours
  • No development reported Lymphoma

Most Recent Events

  • 17 Jun 2026 Efficacy data from a phase I/II trial in Acute myeloid leukaemia released by Akeso Biopharma
  • 02 Jun 2026 Efficacy and adverse events data from a phase I/II trial in Solid tumours presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
  • 15 May 2026 Efficacy and adverse events data from a phase Ib/II trial in Acute myeloid leukemia released by Akeso Biopharma

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