Anti-BACE1/Tau antibody - Denali Therapeutics/Takeda

Drug Profile

Anti-BACE1/Tau antibody - Denali Therapeutics/Takeda

Alternative Names: ATV:BACE1/Tau

Latest Information Update: 23 Mar 2018

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At a glance

  • Originator Denali Therapeutics Inc
  • Class Antidementias; Bispecific antibodies; Neuroprotectants
  • Mechanism of Action BACE1 protein inhibitors; Tau protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Alzheimer's disease

Most Recent Events

  • 23 Mar 2018 Denali Therapeutics intends to file an IND or CTA application in 2020
  • 05 Jan 2018 Takeda and Denali Therapeutics enter into an option and collaboration agreement to develop and commercialise therapeutics for neurodegenerative diseases
  • 01 Jan 2018 Pharmacodynamics data from a preclinical trial in Alzheimer's disease released by Denali Therapeutics
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