Research programme: neurodegenerative disorders antibody therapeutics - Prothena/Celgene
Latest Information Update: 19 Mar 2026
At a glance
- Originator Prothena
- Developer Celgene Corporation; Prothena
- Class Antibodies; Neuroprotectants
- Mechanism of Action Protein folding modulators; TDP-43 protein modulators
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Preclinical Neurodegenerative disorders
Most Recent Events
- 19 Mar 2026 Neurodegenerative disorders antibody therapeutics are still in preclinical development
- 28 Mar 2024 No recent reports of development identified for preclinical development in Neurodegenerative-disorders in Ireland (Parenteral)
- 24 Feb 2020 Preclinical trials in Neurodegenerative disorders in Ireland (Parenteral)