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JNJ 73763989

Drug Profile

JNJ 73763989

Alternative Names: ARO-HBV; JNJ-3989; JNJ-73763989

Latest Information Update: 29 Aug 2022

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At a glance

  • Originator Arrowhead Pharmaceuticals
  • Developer Arrowhead Pharmaceuticals; Janssen Pharmaceuticals; Janssen Sciences Ireland UC
  • Class Amino sugars; Antivirals; Drug conjugates; Small interfering RNA
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatitis B; Hepatitis D

Most Recent Events

  • 29 Aug 2022 Pharmacodynamics and pharmacokinetics data from a phase IIb trial in Hepatitis B presented at the International Liver Congress 2022 (ILC-2022)
  • 25 Jul 2022 Johnson and Johnson intends to submit regulatory application in Hepatitis B and Hepatitis D infection till 2025 (Johnson and Johnson pipeline, July 2025)
  • 22 Jun 2022 Updated efficacy and safety data from the phase II REEF-2 trial in Hepatitis B presented at the International Liver Congress 2022 (ILC-2022)
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