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JHU 395

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Drug Profile

JHU 395

Alternative Names: CNS penetrating glutamine antagonist - Dracen Pharmaceuticals; JHU-395

Latest Information Update: 28 Sep 2024

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At a glance

  • Originator Dracen Pharmaceuticals
  • Class Amines; Antineoplastics; Aza compounds; Caproates; Small molecules
  • Mechanism of Action Apoptosis stimulants; Glutamine inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Medulloblastoma; Neurofibrosarcoma

Most Recent Events

  • 28 Sep 2024 No recent reports of development identified for preclinical development in Medulloblastoma in USA (PO)
  • 28 Sep 2024 No recent reports of development identified for preclinical development in Neurofibrosarcoma in USA (PO)
  • 22 Sep 2022 Preclinical development is still ongoing for Medulloblastoma and Neurofibrosarcoma in USA (Dracen Pharmaceuticals website, September 2022)

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