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TPST 1495

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Drug Profile

TPST 1495

Alternative Names: TPST-1495

Latest Information Update: 22 Aug 2025

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At a glance

  • Originator Tempest Therapeutics
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Prostaglandin E EP2 receptor antagonists; Prostaglandin E EP4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Familial adenomatous polyposis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Familial adenomatous polyposis
  • No development reported Solid tumours

Most Recent Events

  • 11 Aug 2025 Phase I trials in Familial adenomatous polyposis (PO)
  • 28 Jul 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (PO)
  • 28 Jul 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy) in USA (PO)

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