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Descartes 15

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Drug Profile

Descartes 15

Alternative Names: Anti-BCMA mRNA CAR-T cell therapy - Cartesian Therapeutics; Anti-BCMA mRNA chimeric antigen receptor T cell therapy - Cartesian Therapeutics; Descartes-015; Descartes-15

Latest Information Update: 22 Jan 2025

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At a glance

  • Originator Cartesian Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Multiple myeloma
  • Preclinical Autoimmune disorders; Solid tumours
  • Discontinued Systemic lupus erythematosus

Most Recent Events

  • 13 Jan 2025 Cartesian Therapeutics plans a clinical trial in Autoimmune disorders
  • 01 Mar 2024 Phase-I clinical trials in Multiple myeloma (Second-line therapy or greater) in USA (Parenteral) (NCT06304636)
  • 08 Jan 2024 US FDA approves IND application for Descartes 15 in Autoimmune disorders and Multiple myeloma

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