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Crisantaspase biobetter - Jazz Pharmaceuticals/Primrose Bio

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Drug Profile

Crisantaspase biobetter - Jazz Pharmaceuticals/Primrose Bio

Alternative Names: Extended half-life recombinant crisantaspase-Jazz/Primrose Bio; JZP-341; Long-acting Erwinia asparaginase - Jazz Pharmaceuticals/Primrose Bio; PF 745

Latest Information Update: 28 Dec 2024

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At a glance

  • Originator Pfenex
  • Developer Jazz Pharmaceuticals Inc; Primrose Bio
  • Class Amidohydrolases; Antineoplastics; Biobetters; Cytostatics
  • Mechanism of Action Asparaginase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours
  • No development reported Haematological malignancies

Most Recent Events

  • 28 Dec 2024 No recent reports of development identified for preclinical development in Haematological-malignancies in USA
  • 24 Apr 2024 Jazz Pharmaceuticals terminates a phase-I trial in Solid tumours in USA based on a business decision (NCT05631327)
  • 18 Sep 2023 Primordial Genetics has merged with Pelican Expression Technology to form Primrose Bio

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