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Locnartecan - Tarveda Therapeutics

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Drug Profile

Locnartecan - Tarveda Therapeutics

Alternative Names: HDC SN-38; PEN-866; STA-12-8666; STA-8666

Latest Information Update: 01 Jan 2022

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At a glance

  • Originator Madrigal Pharmaceuticals
  • Developer Tarveda Therapeutics
  • Class Alkaloids; Antineoplastics; Camptothecins; Drug conjugates; Indolizines; Pyrans; Quinolines; Small molecules
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 18 May 2021 National Cancer Institute plans a phase I/II trial for Solid tumours (In adults, In adolescents, Combination therapy, Second-line therapy or greater) in USA (IV) (NCT04890093)
  • 18 Mar 2021 Phase I/II development is ongoing in Solid tumours in USA (Tarveda Therapeutics pipeline, March 2021)
  • 31 Dec 2020 Chemical structure information added

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