Drug Profile

Abiprubart - Kiniksa Pharmaceuticals

Alternative Names: KPL-404

Latest Information Update: 07 Apr 2025

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At a glance

Originator Primatope Therapeutics
Developer Kiniksa Pharmaceuticals
Class Antirheumatics; Monoclonal antibodies
Mechanism of Action CD40 antigen inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Autoimmune disorders; Rheumatoid arthritis; Sjogren's syndrome

Most Recent Events

01 Feb 2025 Discontinued - Phase-I for Autoimmune disorders (In volunteers, In adults) in Australia (IV)
01 Feb 2025 Discontinued - Phase-I for Autoimmune disorders (In volunteers, In adults) in Australia (SC)
01 Feb 2025 Discontinued - Phase-I for Autoimmune disorders (In volunteers, In adults) in USA (IV)

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