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Abiprubart - Kiniksa Pharmaceuticals

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Drug Profile

Abiprubart - Kiniksa Pharmaceuticals

Alternative Names: KPL-404

Latest Information Update: 30 May 2025

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At a glance

  • Originator Beth Israel Deaconess Medical Center
  • Developer Kiniksa Pharmaceuticals
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action CD40 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Rheumatoid arthritis
  • No development reported Autoimmune disorders
  • Discontinued Sjogren's syndrome

Most Recent Events

  • 01 Feb 2025 Kiniksa Pharmaceuticals terminates phase II trial in Sjogren's syndrome due to sponsor's decision (SC)
  • 01 Feb 2025 Discontinued - Phase-II for Sjogren's syndrome (SC)
  • 28 Jan 2025 No recent reports of development identified for phase-I development in Autoimmune-disorders(In volunteers, In adults) in Australia (IV)

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