Ubamatamab - Regeneron Pharmaceuticals
Alternative Names: Anti MUC16-CD3 antibody; Anti-MUC16/CD3-BiTE-antibody-REGN4018; antiMUC16-antiCD3-monoclonal-antibodies; Bispecific-T-cell-engager-antibody-REGN-4018; BiTE-antibody-REGN-4018; MUC16xCD3-bispecific-monoclonal-antibodies; REGN4018Latest Information Update: 29 Jan 2025
At a glance
- Originator Regeneron Pharmaceuticals
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Ovarian cancer; Renal cancer; Sarcoma
- Phase I/II Fallopian tube cancer; Peritoneal cancer
Most Recent Events
- 29 Jan 2025 Regeneron Pharmaceuticals plans a phase II trial for Ovarian Cancer () in (Country) (Ref), (NCT ref)
- 22 Jan 2025 Regeneron Pharmaceuticals plans a phase II trial for Ovarian cancer, Peritoneal cancer and Fallopian tube cancer (Monotherapy, Combination therapy, Late-stage disease, Second-line therapy or greater) in May 2025 (NCT06787612)
- 09 Oct 2024 Phase-II clinical trials in Renal cancer (In adolescents, In the elderly, Late-stage disease, Metastatic disease, Second-line therapy or greater, In adults, Combination therapy) in USA (IV) (NCT06444880)