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Alogabat - Genentech

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Drug Profile

Alogabat - Genentech

Alternative Names: GABA-Aa5 PAM; RG-7816; RG7816 alogabat; RO-7017773

Latest Information Update: 25 Jul 2025

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At a glance

  • Originator Roche
  • Class Behavioural disorder therapies; Small molecules
  • Mechanism of Action GABA A alpha 5 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Autism spectrum disorder

Most Recent Events

  • 30 Apr 2025 Roche intends to submit regulatory application for Angelman syndrome, in or after 2028 (Roche pipeline, April 2025)
  • 17 May 2024 Hoffmann-La Roche completes a phase II trial in Autism spectrum disorder (In adolescents, In adults) in USA, Canada, Italy and Spain (PO) (NCT04299464)
  • 09 May 2024 Roche intends to submit regulatory application for Autism spectrum disorder, in or after 2027 (Roche pipeline, May 2024)

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