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Debio 1124

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Drug Profile

Debio 1124

Alternative Names: [177Lu] labelled-minigastrin-analogue; Debio1124; Lutetium-177 minigastrin analogue; Minigastrin analogue (177-Lu) labeled; PPF11N

Latest Information Update: 26 Aug 2022

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At a glance

  • Originator Paul Scherrer Institut
  • Developer Debiopharm; Paul Scherrer Institut
  • Class Antineoplastics; Drug conjugates; Imaging agents; Peptides; Radiopharmaceutical diagnostics; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters; Radionuclide imaging enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Small cell lung cancer; Thyroid cancer

Most Recent Events

  • 11 Jul 2022 Debiopharm returned rights of Debio 1124 to Paul Scherrer Institute (PSI)
  • 11 Jul 2022 Discontinued - Phase-I for Small cell lung cancer (Inoperable/Unresectable, Late-stage disease) in Switzerland (Parenteral)
  • 11 Jul 2022 Discontinued - Phase-I for Thyroid cancer (Diagnosis) in Switzerland (Parenteral)

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