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Certepetide - Lisata Therapeutics

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Drug Profile

Certepetide - Lisata Therapeutics

Alternative Names: CEND-1; Internalised-arginylglycylaspartic Acid Cyclic Peptide; iRGD; LSTA-1

Latest Information Update: 09 Sep 2024

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At a glance

  • Originator DrugCendR
  • Developer Australasian Gastro-Intestinal Trials Group; Lisata Therapeutics; National Health and Medical Research Council Clinical Trials Centre; Qilu Pharmaceutical; The University of Kansas Cancer Center; University of Sydney
  • Class Antineoplastics; Cyclic peptides; Peptides
  • Mechanism of Action Capillary permeability stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Osteosarcoma; Glioma; Cholangiocarcinoma; Pancreatic cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Adenocarcinoma; Glioblastoma; Pancreatic cancer; Solid tumours
  • Phase I/II Colorectal cancer; Gastrointestinal cancer

Most Recent Events

  • 05 Sep 2024 Certepetide - Lisata Therapeutics receives Orphan Drug status for Cholangiocarcinoma in USA
  • 12 Aug 2024 Lisata Therapeutics plans a phase I/II FORTIFIDE trial for Adenocarcinoma (Pancreatic ductal adenocarcinoma) (Second-line or greater, Adjunctive treatment, Metastatic disease) in USA in first half of 2025
  • 16 Jul 2024 Lisata Therapeutics completed enrolment in the phase IIa BOLSTER Trial of Certepetide in First-Line Cholangiocarcinoma in the US and Spain

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