Clesrovimab - Merck Sharp & Dohme
Alternative Names: Anti RSV F antibody - Merck Sharp & Dohme; MK-1654Latest Information Update: 17 Jul 2024
At a glance
- Originator Merck Sharp & Dohme
- Class Antivirals; Monoclonal antibodies
- Mechanism of Action Viral fusion protein inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Respiratory syncytial virus infections
Most Recent Events
- 09 Jul 2024 Merck Sharp & Dohme completes the phase II/III MK-1654-004 trial in Respiratory syncytial virus infections (In infants, In neonates, Prevention) in USA, France, Finland, South Africa, Chile, Colombia, South Korea, Argentina, Canada, Belgium, China, Denmark, Israel, Italy, Malaysia, Mexico, Peru, Poland, Philippines, Romania, Turkey, Thailand, United Kingdom (NCT04767373) (EudraCT2020-002405-26)
- 14 Sep 2022 Merck Sharp & Dohme completes a phase I/II trial in Respiratory tract infections (In infants; In neonates; Prevention) in USA, Chile, Colombia, South Korea, South Africa, Spain (IM) (NCT03524118) (EudraCT2017-005062-21)
- 17 Feb 2022 Merck completes a phase I trial in Respiratory syncytial virus infections (In adults, Prevention)