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Sabizabulin - Veru Healthcare

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Drug Profile

Sabizabulin - Veru Healthcare

Alternative Names: APP-111; Bisindole; VERU-111

Latest Information Update: 09 Aug 2024

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At a glance

  • Originator Ohio State University; University of Tennessee Research Foundation
  • Developer University of Tennessee Research Foundation; Veru Healthcare
  • Class Anti-inflammatories; Antineoplastics; Antivirals; Imidazoles; Indoles; Ketones; Phenyl ethers; Small molecules
  • Mechanism of Action Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Ebola virus infections; Smallpox
  • Preclinical HER2 positive breast cancer
  • Suspended COVID 2019 infections; Influenza A virus H1N1 subtype; SARS-CoV-2 acute respiratory disease
  • No development reported Solid tumours
  • Discontinued Prostate cancer

Most Recent Events

  • 09 Aug 2024 Discontinued - Phase-III for Prostate cancer (Hormone refractory, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
  • 07 Aug 2024 Suspended - Phase-II for SARS-COV-2 acute respiratory disease in USA (PO)
  • 07 Aug 2024 Suspended - Phase-III for COVID-2019 infections in Argentina (PO)

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