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Drug Profile


Alternative Names: XCUR17

Latest Information Update: 13 Dec 2019

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At a glance

  • Originator Exicure
  • Developer Dermelix Biotherapeutics; Exicure
  • Class Anti-inflammatories; Antifibrotics; Antipsoriatics; Antisense oligonucleotides; Nucleic acids; Skin disorder therapies
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Psoriasis
  • Preclinical Alopecia; Congenital ichthyosiform erythroderma

Most Recent Events

  • 14 Nov 2019 Exicure and Allergan agree to co-develop and enter option agreement for SNA based alopecia therapeutics for Alopecia
  • 16 Oct 2019 Additional efficacy data from a phase I trial in Psoriasis released by Exicure
  • 14 Oct 2019 Pharmacodynamics data from a preclinical study in Psoriasis released by Exicure
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