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Navepegritide - Ascendis Pharma

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Drug Profile

Navepegritide - Ascendis Pharma

Alternative Names: ACP-015; C-type natriuretic peptide prodrug - Ascendis Pharma; Navepegritide; Navepegritide- Ascendis Pharma; TransCon C-type natriuretic peptide; TransCon CNP; Yuviwel

Latest Information Update: 21 Apr 2026

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At a glance

  • Originator Ascendis Pharma
  • Developer Ascendis Pharma; VISEN Pharmaceuticals
  • Class Natriuretic peptides
  • Mechanism of Action C-type natriuretic replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Achondroplasia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Achondroplasia

Most Recent Events

  • 08 Apr 2026 Updated efficacy data from the phase II COACH trial in Achondroplasia released by Ascendis Pharma
  • 07 Apr 2026 Launched for Achondroplasia (In children) in USA (SC)
  • 16 Mar 2026 Efficacy and adverse events data from the phase II/III ApproaCH trial in Achondroplasia released by Ascendis Pharma

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