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Denfivontinib - Genosco

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Drug Profile

Denfivontinib - Genosco

Alternative Names: G-801; SKI-G-801

Latest Information Update: 28 Feb 2025

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At a glance

  • Originator Genosco
  • Developer Oscotec
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Axl receptor tyrosine kinase inhibitors; Fms-like tyrosine kinase 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Acute myeloid leukaemia; Solid tumours

Most Recent Events

  • 28 Feb 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Monotherapy) in South Korea (PO)
  • 28 Apr 2024 No recent reports of development identified for phase-I development in Acute-myeloid-leukaemia(Second-line therapy or greater) in USA (IV, Infusion)
  • 18 Apr 2022 SKI G 801 is still in phase I trials for Acute myeloid leukaemia in USA (Genosco pipeline, April 2022)

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