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Ragistomig - ABL Bio/NovaBridge Biosciences

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Drug Profile

Ragistomig - ABL Bio/NovaBridge Biosciences

Alternative Names: ABL-503; TJ L14B

Latest Information Update: 15 Dec 2025

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At a glance

  • Originator I-MAB Biopharma
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; B7-H1 antigen inhibitors; CD137 antigen agonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 10 Dec 2025 Adverse events, efficacy and pharmacodynamic data from a phase I trial in Solid tumours released by NovaBridge .
  • 21 Nov 2025 Ragistomig is still in phase I trials for Solid Tumors (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (NCT04762641)
  • 30 Oct 2025 I-MAB Biopharma is now called NovaBridge Biosciences

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