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LAVA 051

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Drug Profile

LAVA 051

Alternative Names: LAVA-051

Latest Information Update: 28 Aug 2023

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At a glance

  • Originator VU University Medical Center
  • Developer Lava Therapeutics
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Multiple myeloma; Solid tumours

Most Recent Events

  • 22 Aug 2023 Discontinued - Phase-I/II for Acute myeloid leukaemia (Second-line therapy or greater) in Netherlands, Italy, Spain, USA, France (IV) (before August 2023) (Lava Therapeutics Pipeline, August 2023)
  • 22 Aug 2023 Discontinued - Phase-I/II for Chronic lymphocytic leukaemia (Second-line therapy or greater) in Netherlands, Italy, Spain, USA, France (IV) (before August 2023) (Lava Therapeutics Pipeline, August 2023)
  • 22 Aug 2023 Discontinued - Phase-I/II for Multiple myeloma (Second-line therapy or greater) in Netherlands, Italy, Spain, USA, USA, France (IV) (before August 2023) (Lava Therapeutics Pipeline, August 2023)

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