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Apitegromab - Scholar Rock

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Drug Profile

Apitegromab - Scholar Rock

Alternative Names: SRK-015

Latest Information Update: 01 Jul 2025

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At a glance

  • Originator Scholar Rock
  • Class Monoclonal antibodies; Obesity therapies
  • Mechanism of Action Myostatin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinal muscular atrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Spinal muscular atrophy
  • Phase II Obesity
  • No development reported Muscular atrophy; Spinal cord injuries

Most Recent Events

  • 18 Jun 2025 Efficacy and adverse events data from a phase-II EMBRAZE trial in Obesity (Adjunctive treatment) released by Scholar Rock
  • 14 May 2025 Scholar Rock plans to initiate launch Apitegromab for Spinal muscular atrophy in Europe in 2026
  • 28 Mar 2025 Preregistration for Spinal muscular atrophy (In adolescents, In children, In adults) in European Union (IV)

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