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Casdozokitug - Coherus BioSciences/Surface Oncology

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Drug Profile

Casdozokitug - Coherus BioSciences/Surface Oncology

Alternative Names: Anti-IL-27 antibody - Coherus BioSciences; casdozo; CHS-388; IL-27 Blocking Antibody - Coherus BioSciences; SRF-388

Latest Information Update: 03 Jul 2025

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At a glance

  • Originator Surface Oncology
  • Developer Coherus BioSciences; Merck & Co; Roche; Surface Oncology
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Interleukin-27 inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Liver cancer; Non-small cell lung cancer; Renal cell carcinoma

Most Recent Events

  • 23 Jan 2025 Efficacy and adverse events data from phase II trial in Liver cancer presented at the Gastrointestinal Cancers Symposium (ASCO-GI-2025)
  • 23 Dec 2024 9432543 - KDM updated, dev line added for unknown location can change to specific once mentioned in the trial NCT06679985, trial initiation date taken from the MR, FE completed
  • 18 Dec 2024 Phase-II clinical trials in Liver cancer (Combination therapy, First-line therapy, Inoperable/Unresectable, Metastatic disease, Late-stage disease) in USA (IV) (NCT06679985)

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