Drug Profile
Vudalimab - Xencor
Alternative Names: PD-1 x CTLA-4 - Xencor; XmAb 717; XmAb-20717Latest Information Update: 04 Mar 2024
Price :
$50
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At a glance
- Originator Xencor
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T-lymphocyte antigen 4 inhibitors; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Biliary cancer; Gynaecological cancer; Prostate cancer; Urogenital cancer
- Phase I/II Non-small cell lung cancer
Most Recent Events
- 27 Feb 2024 Efficacy and adverse events data from a phase II trial in Prostate cancer released by Xencor
- 13 Feb 2024 M.D. Anderson Cancer Center in collaboration with Xencor withdrew phase II RX-CROME trial prior to enrolment in Colorectal cancer (IV) (NCT05900648)
- 27 Dec 2023 Phase-I/II clinical trials in Non-small cell lung cancer (First-line therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Combination therapy) in USA (IV) (Xencor pipeline; December 2023) (NCT06173505)