Narlumosbart - CSPC Pharmaceutical Group
Alternative Names: Anti-RANKL monoclonal antibody - CSPC Pharmaceutical Group; Jinlitai; JMT-103; Narlumosbart - Shanghai Jinmante BiotechnologyLatest Information Update: 20 Jul 2024
At a glance
- Originator Yong Shun Technology Development
- Developer CSPC Pharmaceutical Group; Shanghai Jinmante Biotechnology
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies; Osteoporosis therapies
- Mechanism of Action RANK ligand inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Registered Giant cell tumour of bone
- Phase II Bone metastases; Postmenopausal osteoporosis
- Discontinued Malignant hypercalcaemia
Most Recent Events
- 31 May 2024 Efficacy and adverse events data from a phase Ib trial in Bone metastases presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
- 01 Feb 2024 Shanghai JMT-Bio plans a phase III trial for Bone metastases in China [SC,Injection] in April 2024 (NCT06221072)
- 13 Oct 2023 Discontinued - Clinical-Phase-Unknown for Malignant hypercalcaemia in China (SC) prior to October 2023 (CSPC Pharmaceuticals pipeline, October 2023)