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Gamcemetinib - Bristol-Myers Squibb

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Drug Profile

Gamcemetinib - Bristol-Myers Squibb

Alternative Names: BMS-986371; CC-99677

Latest Information Update: 07 Apr 2025

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At a glance

  • Originator Celgene Corporation
  • Class Anti-inflammatories
  • Mechanism of Action MAP-kinase-activated kinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Ankylosing spondylitis; Inflammation

Most Recent Events

  • 14 Nov 2024 Efficacy and adverse events data from a phase II trial in Ankylosing Spondylitis presented at the ACR Convergence 2024 (ACR-2024)
  • 27 Mar 2024 Pharmacokinetics and adverse events data from a phase I trial (In volunteers) presented at the 125th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics 2024 (ASCPT-2024)
  • 26 Oct 2023 Discontinued - Phase-I for Inflammation (In volunteers) in USA, United Kingdom (PO) prior to October 2023 (Bristol-Myers Squibb pipeline, October 2023)

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