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BLD 2660

Drug Profile

BLD 2660

Alternative Names: BLD-2660

Latest Information Update: 16 Sep 2020

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At a glance

  • Originator Blade Therapeutics
  • Class Antifibrotics; Small molecules
  • Mechanism of Action Calpain inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II COVID 2019 infections
  • Phase I Idiopathic pulmonary fibrosis
  • Preclinical Interstitial lung diseases

Most Recent Events

  • 14 Sep 2020 Blade Therapeutics completes enrolment in the phase II BLADE-CONQUER trial for COVID-2019 infections in USA and Brazil (PO) (NCT04334460)
  • 01 Sep 2020 Blade Therapeutics suspends prior to enrolment a phase IIa trial in Idiopathic pulmonary fibrosis in the United Kingdom (PO) (owing to COVID-2019 patient safety concerns) (NCT04244825)
  • 04 May 2020 Phase-II clinical trials in COVID-2019 infections in Brazil (PO) (NCT04334460)
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