Inobrodib - CellCentric
Alternative Names: CCS-1477Latest Information Update: 06 Aug 2025
At a glance
- Originator CellCentric
- Class Antineoplastics; Fluorobenzenes; Imidazoles; Isoxazoles; Piperidines; Small molecules
- Mechanism of Action P300-CBP transcription factor inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Acute myeloid leukaemia; Multiple myeloma; Myelodysplastic syndromes; Non-Hodgkin's lymphoma; Prostate cancer; Solid tumours
- Preclinical Malignant melanoma
- No development reported Bladder cancer; Lung cancer
Most Recent Events
- 31 Jul 2025 CellCentric plans a phase II trial for Multiple myeloma (Second-line therapy or greater, Combination therapy) in United Kingdom (PO) in December 2025 (NCT07096778)
- 06 Jul 2025 CellCentric completes phase-I/II clinical trials in Solid tumours (Late-stage disease, Combination therapy) in USA, Sweden, Spain, Netherlands, France, United Kingdom (PO) (NCT03568656)
- 19 May 2025 CellCentric plans accelerated approval pathway for Multiple myeloma