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Inobrodib - CellCentric

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Drug Profile

Inobrodib - CellCentric

Alternative Names: CCS-1477

Latest Information Update: 25 Nov 2025

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At a glance

  • Originator CellCentric
  • Class Antineoplastics; Fluorobenzenes; Imidazoles; Isoxazoles; Piperidines; Small molecules
  • Mechanism of Action P300-CBP transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple myeloma
  • Phase I/II Acute myeloid leukaemia; Myelodysplastic syndromes; Non-Hodgkin's lymphoma; Prostate cancer; Solid tumours
  • Preclinical Malignant melanoma
  • No development reported Bladder cancer; Lung cancer

Most Recent Events

  • 03 Nov 2025 Phase-II clinical trials in Multiple myeloma (Combination therapy, Second-line therapy or greater) in United Kingdom (PO) prior to November 2025 (NCT07096778)
  • 03 Nov 2025 Efficacy and adverse events data from the phase II DoMMino-1 trial in Multiple myeloma released by CellCentric
  • 31 Jul 2025 CellCentric plans a phase II trial for Multiple myeloma (Second-line therapy or greater, Combination therapy) in United Kingdom (PO) in December 2025 (NCT07096778)

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