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Nivolumab/relatlimab - Bristol-Myers Squibb

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Drug Profile

Nivolumab/relatlimab - Bristol-Myers Squibb

Alternative Names: BMS-936558/BMS-986016; BMS-986213; Nivolumab and relatlimab-rmbw - Bristol-Myers Squibb; Nivolumab/relatlimab-rmbw - Bristol Myers Squibb; Opdualag; Relatlimab-rmbw/nivolumab - Bristol Myers Squibb; Relatlimab/nivolumab - Bristol Myers Squibb

Latest Information Update: 27 Jul 2026

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At a glance

  • Originator Bristol-Myers Squibb
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD223 antigen inhibitors; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malignant melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Malignant melanoma
  • Phase III Colorectal cancer; Gastric cancer; Non-small cell lung cancer
  • Phase II Squamous cell cancer
  • Phase I/II Solid tumours
  • No development reported Haematological malignancies

Most Recent Events

  • 29 May 2026 Efficacy and adverse events data from a phase II/III RELATIVITY-047 trial in Malignant melanoma presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
  • 29 May 2026 Efficacy and adverse events data from a phase II/III RELATIVITY-047 trial in Malignant melanoma presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
  • 22 Apr 2026 Efficacy, adverse events, pharmacokinetics and immunogenicity data from a phase I/IIa RELATIVITY-020 trial in Solid tumours presented at the 117th Annual Meeting of the American Association for Cancer Research (AACR-2026)

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