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Nivolumab/relatlimab - Bristol-Myers Squibb

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Drug Profile

Nivolumab/relatlimab - Bristol-Myers Squibb

Alternative Names: BMS-936558/BMS-986016; BMS-986213; Nivolumab and relatlimab-rmbw - Bristol-Myers Squibb; Nivolumab/relatlimab-rmbw - Bristol Myers Squibb; Opdualag; Relatlimab-rmbw/nivolumab - Bristol Myers Squibb; Relatlimab/nivolumab - Bristol Myers Squibb

Latest Information Update: 23 Aug 2024

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At a glance

  • Originator Bristol-Myers Squibb
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD223 antigen inhibitors; Programmed cell death 1 receptor antagonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Malignant melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Malignant melanoma
  • Phase III Colorectal cancer; Gastric cancer; Solid tumours
  • Phase II Squamous cell cancer
  • Phase I Haematological malignancies

Most Recent Events

  • 23 Aug 2024 Bristol-Myers Squibb plans a phase III RELATIVITY1093 trial for Non-small Cell Lung Cancer (Combination therapy, Recurrent, Late-stage disease, First-line therapy) in USA, Argentina, Australia, Austria, Belgium, Brazil, Chile, China, Denmark, France, Germany, India, Italy, Japan, South Korea, Netherlands, Poland, Romania, Spain, Switzerland, Taiwan, and the United Kingdom in September 2024 (NCT06561386)
  • 18 Jan 2024 Bristol-Myers Squibb completes a phase-II clinical trials in Gastric cancer (Adjunctive treatment, First-line therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA, Argentina, Belgium, Canada, Chile, France, Germany, Italy, Norway, Puerto Rico, Singapore, Spain, United Kingdom, Australia, Austria, Czhezia, Poland(IV) (NCT03662659)
  • 08 Nov 2023 Bristol-Myers Squibb initiates enrolment in the phase II trial for Malignant melanoma (First-line therapy, Late-stage disease, Metastatic disease) in USA (IV)

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