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Pegarginase - Athenex

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Drug Profile

Pegarginase - Athenex

Alternative Names: Pegtomarginase; Pegylated arginase - Athenex; Pegylated Modified Human Arginase; PT01

Latest Information Update: 17 Apr 2024

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At a glance

  • Originator Hong Kong Polytechnic University
  • Developer Athenex
  • Class Antineoplastics; Polyethylene glycols; Ureohydrolases
  • Mechanism of Action Arginase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 12 Sep 2023 Discontinued - Phase-I for Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease) in USA (IV)
  • 30 Mar 2022 Athenex suspends enrolment in a phase-I trial in Solid tumours (Inoperable/Unresectable, Metastatic disease, Late-stage disease) in USA (IV) (NCT04136834)
  • 21 Apr 2021 Phase-I clinical trials in Solid tumours (Inoperable/Unresectable, Metastatic disease, Late-stage disease) in USA (IV) (NCT04136834)

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