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Orforglipron - Eli Lilly and Company

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Drug Profile

Orforglipron - Eli Lilly and Company

Alternative Names: GLP-1 receptor NPA - Eli Lilly and Company; Glucagon like peptide 1 receptor NPA - Eli Lilly and Company; LY-3502970; OWL 833

Latest Information Update: 02 Dec 2024

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At a glance

  • Originator Chugai Pharmaceutical
  • Developer Eli Lilly and Company
  • Class Antihyperglycaemics; Fluorinated hydrocarbons; Imidazoles; Indazoles; Indoles; Ketones; Obesity therapies; Oxadiazoles; Pyrazoles; Pyridines; Small molecules
  • Mechanism of Action Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Obesity; Type 2 diabetes mellitus

Most Recent Events

  • 26 Nov 2024 Eli Lilly and Company plans a phase I pharmacokinetics trial (In volunteers) in USA (PO) (NCT06704763)
  • 18 Nov 2024 Phase-III clinical trials in Obesity (In children, In adolescents) in United Kingdom, Mexico, Japan, Israel, Brazil, USA (PO) (NCT06672939) (EUCT-2024-514081-40-00)
  • 18 Nov 2024 Eli Lilly and Company completes a phase I pharmacokinetics trial in participants with Hepatic impairment and healthy volunteers in USA (PO) (NCT05882032)

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